Bioactive Small Molecules
Cayman Chemical C-DIM8, Purity: ≥95%, CAS: 151358-47-3, 50 mg
A Nur77 antagonist; inhibits C-DIM5-induced reporter gene expression in PANC-28 cells at 20 µM; reduces expression of BIRC5 in PANC-1 cells at 10, 15, and 20 µM; induces tumor cell apoptosis and reduces tumor volume in an L3.6pl pancreatic carcinoma mouse xenograft model at 30 mg/kg
Medchemexpress LLC MYCi361 | 2289690-31-7 | MFCD32263412 | 5 mg
MYCi361 | Purity: 99.42% | Mol Wt: 594.86 | 2289690-31-7 | MFCD32263412 | 5 mg
Medchemexpress LLC Tyrosylleucine | 17355-10-1 | 99.9% | 50 MG
Tyrosylleucine (Tyr-Leu, YL) is an orally active dipeptide composed of tyrosine and leucine, reported to exhibit potent antidepressant-like activity. It is supplied as a high-purity white to off-white solid for research use, with specified storage and handling recommendations.
- Sequence Tyr-Leu (dipeptide).
- Cas number 17355-10-1.
- Molecular weight 294.35 g/mol.
- Purity 99.9% (as stated by supplier).
- Appearance white to off-white solid.
- Storage sealed and protected from moisture; powder: -80°C for 2 years, -20°C for 1 year.
- Available in milligram pack sizes, including 50 mg.
Medchemexpress LLC BMS-433771 dihydrochloride hydrate | 543700-67-0 | 98.0% | 1 ML
This dihydrochloride hydrate is a respiratory syncytial virus (RSV) fusion inhibitor supplied as a 10 mM solution in DMSO for research use. It is provided with supporting analytical data and handling guidance.
- Orally active RSV fusion inhibitor.
- Supplied as 10 mM solution in DMSO, 1 ML.
- Purity 98.0%.
- Molecular weight 468.38 g/mol.
- Appearance off-white to light yellow solid (supplied as solution).
- Storage in solvent: -80°C up to 6 months, -20°C up to 1 month.
Medchemexpress LLC 20(S)-hydroxycholesterol | 516-72-3 | MFCD16661190 | 98.7% | 402.7 g/mol | C27H46O2 | 5MG
20(S)-Hydroxycholesterol is an oxysterol used as a research reagent and analytical standard. It acts as an allosteric activator of the Smoothened (Smo) protein in the Hedgehog signaling pathway and is commonly used in developmental biology, oncology, and cell signaling studies. The compound has CAS RN 516-72-3, molecular formula C27H46O2, and molecular weight 402.7 g/mol.
Medchemexpress LLC Eberconazole nitrate | 130104-32-4 | MFCD00896878 | 99.8% | 392.24 | C18H15Cl2N3O3 | 25 MG
Eberconazole nitrate is a dichlorinated imidazole antifungal compound supplied as an analytical standard for research and analytical applications. It is intended for use in qualitative and quantitative assays, method development, and instrument calibration in chromatographic and mass spectrometric workflows.
- High purity analytical standard suitable for reference and calibration.
- Validated by HPLC with purity 99.76%.
- Molecular formula C18H15Cl2N3O3 and molecular weight 392.24 facilitate compound identification.
- Available in multiple pack sizes, including 25 mg, for flexible use.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Beta-sitosterol-d7 (mixture of diastereomers) | 2260669-28-9 | MFCD08704917 | ≥98.0% | C29H43D7O | 10MG
β-Sitosterol-d7 (mixture of diastereomers) is the deuterium-labeled analogue of β-sitosterol provided as a reference material and internal standard for lipid analysis and mass spectrometry. The material contains seven deuterium atoms and is supplied as a white to off-white solid with high isotopic enrichment suitable for GC-MS and LC-MS quantification and method development.
- Deuterium-labeled internal standard for accurate quantification.
- Mixture of diastereomers matching reference analyte behavior.
- High isotopic enrichment (d7) for clear mass separation.
- Suitable for GC-MS and LC-MS method development and validation.
- White to off-white solid, stable under typical storage conditions.
Medchemexpress LLC GLP-2(3-33) | 275801-62-2 | >99.8% | 3557.89 | 5 MG
GLP-2(3-33) is a peptide naturally generated by dipeptidylpeptidase IV (DPPIV). It functions as a partial agonist on the GLP-2 receptor with an EC50 of 5.8 nM and exhibits potential competitive antagonistic properties. This peptide has shown a binding IC50 of 41 nM in GLP-2 receptor-binding assays.
- Naturally generated by dipeptidylpeptidase IV (DPPIV)
- Acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM)
- Exhibits potential competitive antagonistic properties
- Demonstrates binding IC50 of 41 nM in GLP-2 receptor-binding assay
- Increases dyslipidemia and hepatic lipid accumulation in HFD-fed mice in vivo
Cambridge Isotope Laboratories 5-AMINOLEVULINIC ACID:HCL (5-13C, 99%) 96% CHEMICAL PURITY, 0.05 G
5-AMINOLEVULINIC ACID:HCL (5-13C, 99%) 96% CHEMICAL PURITY, 0.05 G
Enzo Life Sciences Ac-LEVD-pNA (5mg)
Chromogenic substrate for caspase-4. Alternative name: Caspase 4 substrate (chromogenic). Formula: C28H40N6O11. MW: 636.7. Purity: ≥99% (HPLC). Solubility: Soluble in buffer, pH 7.0-8.0 (e. g. TRIS, HEPES). Long Term Storage: -20°C.
Medchemexpress LLC HY-B1170 500mg Medchemexpress, Cyclandelate CAS:456-59-7 Purity:>98%
Medchemexpress, HY-B1170 500mg Cyclandelate CAS:456-59-7 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC RJPXD33 | 1613160-77-2 | 98.1% | 1489.78 | 50 MG
RJPXD33 is an inhibitor for LpxD and LpxA with IC50 values of 3.5 μM and 19 μM, respectively. It inhibits LpxD and LpxA in *E. coli* with Kd values of 6 μM and 20 μM.
- Inhibits LpxD and LpxA
- IC50 values of 3.5 μM (LpxD) and 19 μM (LpxA)
- Inhibits LpxD and LpxA in *E. coli* with Kd values of 6 μM and 20 μM
- Appearance: solid
- Color: white to off-white
- Sequence: Thr-Asn-Leu-Tyr-Met-Leu-Pro-Lys-Trp-Asp-Ile-Pro-NH2
- Powder storage: -80°C for 2 years, -20°C for 1 year
- In-solvent storage: -80°C for 6 months, -20°C for 1 month (sealed storage, away from moisture)
Medchemexpress LLC Pittsburgh compound B | 566169-93-5 | 98.0% | 256.33 g·mol⁻1 | C14H12N2OS | 5MG
Pittsburgh Compound B (PiB) is a research-grade PET tracer used to bind and visualize amyloid-β (Aβ) deposits for Alzheimer's disease research. Supplied as a small-molecule solid in milligram-scale quantities, it is intended for preclinical and in vitro studies, imaging assay development, and ligand-binding experiments.
- High purity 98.0% for reproducible experimental results.
- Supplied as 5 mg for small-scale assays and method development.
- Binds amyloid-β enabling PET tracer and imaging applications.
- Molecular formula C14H12N2OS and molecular weight 256.33 g·mol⁻¹ for precise stoichiometry.
- Provided with product datasheet for handling and characterization details.
Medchemexpress LLC Feprazone | 25MG
Feprazone (DA2370 Prenazone) an analogue of Phenylbutazone (HY-B0230) is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2 Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS) Feprazone can decrease the expression of MMP-2 and MMP-9 Besides Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells Feprazone also can be used to research atherosclerosis and obesity[1][2][3]
Medchemexpress LLC Selvigaltin (GB1211) | 1978336-95-6 | 99.9% | 533.32 | 25 MG
Selvigaltin (GB1211) is an orally active small molecule inhibitor of galectin-3. It demonstrates anti-tumor activity and is effective at reducing galectin-3 levels in the liver. It also decreases biomarkers of liver function, inflammation, and fibrosis, while restoring T-cell activity.
- Reduces galectin-3 levels in the liver
- Decreases biomarkers of liver function (AST, ALT, bilirubin)
- Lowers inflammation markers (cells foci)
- Reduces fibrosis biomarkers (PSR, SHG)
- Decreases mRNA and protein expression of IL6, TGFβ3, SNAI2, and collagen
- Restores T-cell activity
- Leads to fewer tumors and metastasis